Pluvicto for Advanced Prostate Cancer

Dr. Michael Guiou, Dr. Kamal Abbi, and Dr. Matthew Ryan discuss Pluvicto, an innovative radiopharmaceutical treatment for advanced prostate cancer that delivers targeted radiation throughout the body with fewer side effects than traditional chemotherapy.

Radiation oncologist Dr. Michael Guiou and medical oncologists Dr. Kamal Abbi and Dr. Matthew Ryan discuss Pluvicto, an innovative radiopharmaceutical treatment for advanced prostate cancer. They explain how this therapy uses a targeted approach to deliver radiation from the inside out, who is eligible for the treatment, and what patients can expect. 

“With external beam radiation, you’re limited in what you can treat… with Pluvicto, you can have things in your pelvis and your chest and your arm and your leg. You can treat all those.” – Dr. Michael Guiou 

In this episode of Cancer Covered, you’ll learn: 

  • Pluvicto is a targeted therapy that delivers a low-traveling dose of radiation directly to prostate cancer cells throughout the body, minimizing damage to surrounding tissue. 
  • This therapy is used for men with metastatic castration-resistant prostate cancer, and its recent FDA approval has expanded its availability to more patients. 
  • While not a cure, Pluvicto has shown significant effectiveness in controlling the disease and improving quality of life, with two-thirds of patients seeing some form of benefit. 
  • The treatment is generally well-tolerated by most patients and often has fewer side effects than chemotherapy. 
  • Patients who receive Pluvicto must take temporary safety precautions for a few days after treatment to limit radiation exposure to others. 

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