How is Breast Cancer Treated?

Dr. Stephanie Fries and Dr. Judy Tjoe break down the modern breast cancer journey, exploring how multidisciplinary care, genomic testing, and cutting-edge therapies enable doctors to replace rigid, one-size-fits-all treatments with compassionate, highly personalized surgical and medical plans.

Dr. Stephanie Fries and Dr. Judy Tjoe sit down to examine what happens following a breast cancer diagnosis and how treatment decisions are tailored to each individual patient. They unpack how modern cancer medicine has moved away from a rigid, one-size-fits-all approach toward personalized care, explain how tumor biology and genomic testing guide choices around chemotherapy and endocrine therapy, and highlight the multidisciplinary teamwork and patient preferences that shape surgical options.

“Even though Dr. Fries and I and our oncological team take care of hundreds of patients with breast cancer every year, we know that this is likely gonna be your first, maybe your second, and we’ll never forget that, and we will be with you every step of the way.” — Dr. Judy Tjoe

In this episode, we cover:

  • The first visit and biopsy breakdown: Why taking time to walk through medical illustrations, anatomy, and pathology reports, including estrogen, progesterone, and HER2 receptor status, is vital for informed, shared decision-making.
  • Personalized surgical options: The choice between lumpectomy and total mastectomy, the role of oncoplastic techniques and nerve-sparing approaches, and how sentinel lymph node biopsies have minimized the risk of lymphedema compared to older surgical methods.
  • Cancer as a team sport: How close daily collaboration among medical oncologists, breast surgeons, radiation oncologists, and weekly multidisciplinary tumor boards ensures every patient’s treatment plan is individually customized.
  • De-escalating therapy and genomic testing: How tools like Oncotype DX and MammaPrint help spare the majority of hormone receptor–positive patients from unnecessary chemotherapy while pinpointing who truly benefits.
  • Emerging treatments and future advances: The excitement around antibody-drug conjugates (ADCs) acting as targeted “Trojan horses” to deliver chemotherapy straight to cancer cells, and how circulating tumor DNA blood tests are evolving to detect residual disease.
  • You are not alone: Reassurance regarding the high cure rates for early-stage breast cancer, the value of routine mammograms, and the compassionate care team ready to support patients at every step.
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